Every nonstop destination from Chicago O'Hare International Airport, with airlines and flight frequency.
Chicago O'Hare International Airport (ORD) in Chicago, United States currently offers nonstop flights to 301 destinations in 43 countries. The airlines operating the most nonstop routes from ORD are United Airlines, American Airlines, Envoy Air, SkyWest Airlines, Delta Air Lines. Route data comes from the AeroDataBox flight database and is regenerated regularly.
76 airlines operate nonstop routes from Chicago O'Hare International Airport. United Airlines serves the most, with 193 nonstop destinations.
| Airline | Nonstop destinations |
|---|---|
| United Airlines | 193 nonstop destinations |
| American Airlines | 159 nonstop destinations |
| Envoy Air | 81 nonstop destinations |
| SkyWest Airlines | 38 nonstop destinations |
| Delta Air Lines | 18 nonstop destinations |
| Frontier Airlines | 11 nonstop destinations |
| Contour Aviation | 7 nonstop destinations |
| Qatar Airways | 7 nonstop destinations |
| Alaska Airlines | 6 nonstop destinations |
| JRE | 6 nonstop destinations |
| China Airlines | 5 nonstop destinations |
| EVA Air | 5 nonstop destinations |
| Sun Country Airlines | 5 nonstop destinations |
| Volaris | 5 nonstop destinations |
| Korean Air | 4 nonstop destinations |
| Republic Airways | 4 nonstop destinations |
| Air Canada | 3 nonstop destinations |
| Air France | 3 nonstop destinations |
| Avianca | 3 nonstop destinations |
| Cathay Pacific | 3 nonstop destinations |
| CSG | 3 nonstop destinations |
| Denver Air Connection | 3 nonstop destinations |
| Emirates | 3 nonstop destinations |
| JetBlue Airways | 3 nonstop destinations |
| Libyan Airlines | 3 nonstop destinations |
| National Airlines | 3 nonstop destinations |
| Turkish Airlines | 3 nonstop destinations |
| VivaAerobus | 3 nonstop destinations |
| VJA | 3 nonstop destinations |
| Aeromexico | 2 nonstop destinations |
| Air Incheon | 2 nonstop destinations |
| Breeze Airways | 2 nonstop destinations |
| COL | 2 nonstop destinations |
| Ethiopian Airlines | 2 nonstop destinations |
| JTZ | 2 nonstop destinations |
| LOT - Polish Airlines | 2 nonstop destinations |
| Lufthansa | 2 nonstop destinations |
| NXC | 2 nonstop destinations |
| Qantas | 2 nonstop destinations |
| RVJ | 2 nonstop destinations |
| Silk Way West | 2 nonstop destinations |
| TAP Air Portugal | 2 nonstop destinations |
| AAE | 1 nonstop destination |
| Aer Lingus | 1 nonstop destination |
| Air China | 1 nonstop destination |
| Air Serbia | 1 nonstop destination |
| ANA | 1 nonstop destination |
| Arajet | 1 nonstop destination |
| Austrian | 1 nonstop destination |
| Avelo Airlines | 1 nonstop destination |
| Avianca Costa Rica | 1 nonstop destination |
| British Airways | 1 nonstop destination |
| China Southern Airlines | 1 nonstop destination |
| Copa Airlines | 1 nonstop destination |
| EgyptAir | 1 nonstop destination |
| Etihad Airways | 1 nonstop destination |
| FF | 1 nonstop destination |
| Finnair | 1 nonstop destination |
| GetJet Airlines | 1 nonstop destination |
| Iberia | 1 nonstop destination |
| Icelandair | 1 nonstop destination |
| ITA Airways | 1 nonstop destination |
| JAL | 1 nonstop destination |
| Japan Airlines | 1 nonstop destination |
| JBD | 1 nonstop destination |
| KLM | 1 nonstop destination |
| LJY | 1 nonstop destination |
| MJS | 1 nonstop destination |
| Royal Jordanian | 1 nonstop destination |
| SAS | 1 nonstop destination |
| SF Airlines | 1 nonstop destination |
| Southwest Airlines | 1 nonstop destination |
| Suparna Airlines | 1 nonstop destination |
| SWISS | 1 nonstop destination |
| TTT | 1 nonstop destination |
| WestJet | 1 nonstop destination |
| Destination | Country | Airlines | Frequency |
|---|---|---|---|
| Los AngelesLAX | United States | American Airlines, Delta Air Lines, Frontier Airlines, Qantas +1 more | 30× daily |
| BostonBOS | United States | American Airlines, Delta Air Lines, Envoy Air, JetBlue Airways +2 more | 30× daily |
| New YorkLGA | United States | American Airlines, United Airlines | 29× daily |
| Dallas-Fort WorthDFW | United States | Air Incheon, American Airlines, Envoy Air, EVA Air +4 more | 27× daily |
| AtlantaATL | United States | Air Incheon, American Airlines, Delta Air Lines, Frontier Airlines +3 more | 24× daily |
| WashingtonDCA | United States | American Airlines, United Airlines | 23× daily |
| SeattleSEA | United States | Alaska Airlines, American Airlines, China Airlines, Delta Air Lines +2 more | 23× daily |
| HoustonIAH | United States | American Airlines, Frontier Airlines, Qatar Airways, Turkish Airlines +1 more | 22× daily |
| DenverDEN | United States | American Airlines, Envoy Air, Frontier Airlines, United Airlines | 22× daily |
| MinneapolisMSP | United States | American Airlines, Delta Air Lines, Envoy Air, Sun Country Airlines +1 more | 22× daily |
| NewarkEWR | United States | American Airlines, United Airlines | 21× daily |
| San FranciscoSFO | United States | American Airlines, United Airlines | 20× daily |
| DetroitDTW | United States | American Airlines, Delta Air Lines, Envoy Air, Republic Airways +1 more | 19× daily |
| TorontoYYZ | Canada | American Airlines, Cathay Pacific, Envoy Air, EVA Air +4 more | 19× daily |
| PhiladelphiaPHL | United States | American Airlines, COL, Frontier Airlines, Sun Country Airlines +1 more | 19× daily |
| Saint LouisSTL | United States | American Airlines, Delta Air Lines, Envoy Air, United Airlines | 18× daily |
| CincinnatiCVG | United States | American Airlines, Delta Air Lines, Envoy Air, United Airlines | 18× daily |
| PhoenixPHX | United States | American Airlines, United Airlines | 17× daily |
| MilwaukeeMKE | United States | American Airlines, Envoy Air, SkyWest Airlines, United Airlines | 17× daily |
| ClevelandCLE | United States | American Airlines, Envoy Air, RVJ, SkyWest Airlines +1 more | 17× daily |
| OrlandoMCO | United States | American Airlines, Frontier Airlines, JTZ, United Airlines | 16× daily |
| CharlotteCLT | United States | American Airlines, United Airlines | 16× daily |
| IndianapolisIND | United States | American Airlines, Envoy Air, Republic Airways, United Airlines | 16× daily |
| Grand RapidsGRR | United States | American Airlines, Envoy Air, United Airlines | 15× daily |
| ColumbusCMH | United States | American Airlines, Envoy Air, United Airlines | 15× daily |
| NashvilleBNA | United States | Alaska Airlines, American Airlines, Envoy Air, United Airlines | 15× daily |
| San DiegoSAN | United States | Alaska Airlines, American Airlines, Sun Country Airlines, United Airlines | 15× daily |
| Las VegasLAS | United States | American Airlines, Frontier Airlines, United Airlines | 15× daily |
| Kansas CityMCI | United States | American Airlines, Envoy Air, United Airlines | 15× daily |
| MadisonMSN | United States | American Airlines, Envoy Air, SkyWest Airlines, United Airlines | 14× daily |
| Traverse CityTVC | United States | American Airlines, Envoy Air, United Airlines | 14× daily |
| Raleigh/DurhamRDU | United States | American Airlines, Envoy Air, United Airlines | 14× daily |
| PittsburghPIT | United States | American Airlines, United Airlines | 14× daily |
| MiamiMIA | United States | American Airlines, United Airlines | 13× daily |
| OmahaOMA | United States | American Airlines, Envoy Air, United Airlines | 12× daily |
| MontrealYUL | Canada | Air Canada, American Airlines, Envoy Air, United Airlines | 11× daily |
| AustinAUS | United States | American Airlines, United Airlines | 11× daily |
| Des MoinesDSM | United States | American Airlines, Envoy Air, United Airlines | 11× daily |
| Green BayGRB | United States | American Airlines, Envoy Air, United Airlines | 11× daily |
| Salt Lake CitySLC | United States | American Airlines, Delta Air Lines, United Airlines | 11× daily |
| AppletonATW | United States | American Airlines, Envoy Air, SkyWest Airlines, United Airlines | 10× daily |
| Cedar RapidsCID | United States | American Airlines, Delta Air Lines, Envoy Air, NXC +1 more | 10× daily |
| KnoxvilleTYS | United States | American Airlines, Envoy Air, SkyWest Airlines, United Airlines | 10× daily |
| LondonLHR | United Kingdom | American Airlines, British Airways, United Airlines | 10× daily |
| Fort LauderdaleFLL | United States | American Airlines, Frontier Airlines, JetBlue Airways, United Airlines | 10× daily |
| LouisvilleSDF | United States | American Airlines, Envoy Air, Republic Airways, United Airlines | 10× daily |
| Mexico CityMEX | Mexico | Aeromexico, American Airlines, United Airlines, VivaAerobus +1 more | 10× daily |
| AnchorageANC | United States | Alaska Airlines, American Airlines, Cathay Pacific, China Airlines +4 more | 9× daily |
| RichmondRIC | United States | American Airlines, Envoy Air, United Airlines | 9× daily |
| MemphisMEM | United States | American Airlines, Envoy Air, SkyWest Airlines, United Airlines | 9× daily |
| MolineMLI | United States | American Airlines, Envoy Air, SkyWest Airlines, United Airlines | 9× daily |
| Fayetteville/Springdale/XNA | United States | American Airlines, Envoy Air, United Airlines | 9× daily |
| AlbanyALB | United States | American Airlines, United Airlines | 9× daily |
| DaytonDAY | United States | American Airlines, Envoy Air, SkyWest Airlines, United Airlines | 9× daily |
| SyracuseSYR | United States | American Airlines, Envoy Air, Republic Airways, SkyWest Airlines +1 more | 9× daily |
| TulsaTUL | United States | American Airlines, Envoy Air, SkyWest Airlines, United Airlines | 9× daily |
| HartfordBDL | United States | American Airlines, United Airlines | 9× daily |
| Oklahoma CityOKC | United States | American Airlines, SkyWest Airlines, United Airlines | 9× daily |
| South BendSBN | United States | Delta Air Lines, SkyWest Airlines, United Airlines | 9× daily |
| BuffaloBUF | United States | American Airlines, SkyWest Airlines, United Airlines | 8× daily |
| JacksonvilleJAX | United States | American Airlines, Delta Air Lines, Envoy Air, SkyWest Airlines +1 more | 8× daily |
| LexingtonLEX | United States | American Airlines, United Airlines | 8× daily |
| BaltimoreBWI | United States | American Airlines, Envoy Air, United Airlines | 8× daily |
| PortlandPDX | United States | Alaska Airlines, Sun Country Airlines, United Airlines | 8× daily |
| Fort WayneFWA | United States | American Airlines, Delta Air Lines, SkyWest Airlines, United Airlines | 8× daily |
| GreenvilleGSP | United States | American Airlines, Envoy Air, United Airlines | 8× daily |
| TampaTPA | United States | American Airlines, JTZ, United Airlines | 8× daily |
| New YorkJFK | United States | Delta Air Lines, JetBlue Airways | 8× daily |
| FargoFAR | United States | American Airlines, Envoy Air, United Airlines | 8× daily |
| HarrisburgMDT | United States | American Airlines, United Airlines | 8× daily |
| AshevilleAVL | United States | American Airlines, Envoy Air, United Airlines | 7× daily |
| CharlestonCHS | United States | American Airlines, Breeze Airways, Envoy Air, United Airlines | 7× daily |
| SpringfieldSGF | United States | American Airlines, Envoy Air, United Airlines | 7× daily |
| ChattanoogaCHA | United States | American Airlines, Envoy Air, United Airlines | 7× daily |
| PeoriaPIA | United States | American Airlines, Envoy Air, SkyWest Airlines, United Airlines | 7× daily |
| Sioux FallsFSD | United States | American Airlines, United Airlines | 7× daily |
| Little RockLIT | United States | American Airlines, Envoy Air, United Airlines | 7× daily |
| AkronCAK | United States | American Airlines, Envoy Air, SkyWest Airlines, United Airlines | 7× daily |
| Fort MyersRSW | United States | American Airlines, United Airlines | 7× daily |
| NorfolkORF | United States | American Airlines, Envoy Air, SkyWest Airlines, United Airlines | 7× daily |
| WichitaICT | United States | American Airlines, Envoy Air, United Airlines | 7× daily |
| New OrleansMSY | United States | American Airlines, Envoy Air, United Airlines | 7× daily |
| Santa AnaSNA | United States | American Airlines, United Airlines | 7× daily |
| RochesterROC | United States | Envoy Air, United Airlines | 7× daily |
| GreensboroGSO | United States | American Airlines, Envoy Air, United Airlines | 6× daily |
| VancouverYVR | Canada | Air Canada, American Airlines, United Airlines | 6× daily |
| AllentownABE | United States | American Airlines, Envoy Air, GetJet Airlines, United Airlines | 6× daily |
| CalgaryYYC | Canada | American Airlines, United Airlines, WestJet | 6× daily |
| Frankfurt-am-MainFRA | Germany | Lufthansa, Qatar Airways, United Airlines | 6× daily |
| LincolnLNK | United States | American Airlines, United Airlines | 6× daily |
| ProvidencePVD | United States | American Airlines, Envoy Air, SkyWest Airlines, United Airlines | 6× daily |
| GuadalajaraGDL | Mexico | Aeromexico, VivaAerobus, Volaris | 6× daily |
| BurlingtonBTV | United States | American Airlines, Envoy Air, United Airlines | 5× daily |
| KalispellFCA | United States | American Airlines, United Airlines | 5× daily |
| BirminghamBHM | United States | American Airlines, United Airlines | 5× daily |
| State CollegeSCE | United States | LJY, United Airlines | 5× daily |
| CancúnCUN | Mexico | American Airlines, Frontier Airlines, United Airlines | 5× daily |
| DublinDUB | Ireland | Aer Lingus, Air France, American Airlines, United Airlines | 5× daily |
| FlintFNT | United States | American Airlines, United Airlines | 5× daily |
| JacksonJAC | United States | American Airlines, United Airlines | 5× daily |
| SeoulICN | South Korea | Korean Air | 5× daily |
| SavannahSAV | United States | American Airlines, Envoy Air, United Airlines | 5× daily |
| BozemanBZN | United States | American Airlines, United Airlines | 5× daily |
| RoanokeROA | United States | American Airlines, Envoy Air, United Airlines | 5× daily |
| DuluthDLH | United States | SkyWest Airlines, United Airlines | 4× daily |
| ParisCDG | France | Air France, American Airlines, United Airlines | 4× daily |
| SacramentoSMF | United States | American Airlines, United Airlines | 4× daily |
| WilmingtonILM | United States | American Airlines, Envoy Air, United Airlines | 4× daily |
| CharlottesvilleCHO | United States | SkyWest Airlines, United Airlines | 4× daily |
| HuntsvilleHSV | United States | American Airlines, Delta Air Lines, United Airlines | 4× daily |
| ReykjavikKEF | Iceland | Icelandair, United Airlines | 4× daily |
| Wilkes-Barre/ScrantonAVP | United States | American Airlines, Envoy Air, United Airlines | 4× daily |
| AspenASE | United States | American Airlines, United Airlines | 4× daily |
| BangorBGR | United States | American Airlines, Envoy Air, United Airlines | 4× daily |
| ColumbiaCOU | United States | American Airlines, Envoy Air, SkyWest Airlines | 4× daily |
| White PlainsHPN | United States | American Airlines, Envoy Air | 4× daily |
| ZurichZRH | Switzerland | SWISS, United Airlines | 4× daily |
| San JuanSJU | Puerto Rico | American Airlines, Frontier Airlines, United Airlines, Southwest Airlines | 4× daily |
| Colorado SpringsCOS | United States | American Airlines, Delta Air Lines, SkyWest Airlines, United Airlines | 4× daily |
| PortlandPWM | United States | American Airlines | 4× daily |
| Rapid CityRAP | United States | American Airlines, Envoy Air, United Airlines | 4× daily |
| TucsonTUS | United States | American Airlines, Delta Air Lines, United Airlines | 4× daily |
| West Palm BeachPBI | United States | American Airlines, United Airlines | 4× daily |
| TokyoNRT | Japan | ANA, Japan Airlines | 4× daily |
| BoiseBOI | United States | American Airlines, United Airlines | 3× daily |
| ColumbiaCAE | United States | United Airlines | 3× daily |
| OttawaYOW | Canada | United Airlines | 3× daily |
| MunichMUC | Germany | Lufthansa, United Airlines | 3× daily |
| RomeFCO | Italy | American Airlines, ITA Airways, United Airlines | 3× daily |
| San AntonioSAT | United States | American Airlines, Envoy Air | 3× daily |
| The Duke CityABQ | United States | American Airlines, United Airlines | 3× daily |
| ManchesterMHT | United States | American Airlines, Envoy Air | 3× daily |
| MarquetteMQT | United States | American Airlines, Envoy Air | 3× daily |
| AmsterdamAMS | Netherlands | KLM, National Airlines, Qatar Airways, United Airlines | 3× daily |
| La CrosseLSE | United States | American Airlines, Envoy Air | 3× daily |
| MosineeCWA | United States | American Airlines, Envoy Air | 3× daily |
| HancockCMX | United States | SkyWest Airlines, United Airlines | 3× daily |
| IstanbulIST | Türkiye | Turkish Airlines | 3× daily |
| PellstonPLN | United States | SkyWest Airlines, United Airlines | 3× daily |
| ShanghaiPVG | China | Air China, China Southern Airlines, CSG, National Airlines | 3× daily |
| WaterlooALO | United States | American Airlines, TTT | 3× daily |
| Abu DhabiAUH | United Arab Emirates | Etihad Airways | 3× daily |
| MadridMAD | Spain | American Airlines, Iberia | 3× daily |
| RochesterRST | United States | American Airlines, JRE | 3× daily |
| TocumenPTY | Panama | Copa Airlines | 3× daily |
| AthensATH | Greece | American Airlines, United Airlines | 2× daily |
| LansingLAN | United States | American Airlines, Envoy Air | 2× daily |
| Myrtle BeachMYR | United States | American Airlines, Envoy Air, United Airlines | 2× daily |
| Panama City BeachECP | United States | American Airlines, Delta Air Lines, United Airlines | 2× daily |
| BarcelonaBCN | Spain | American Airlines, United Airlines | 2× daily |
| ManisteeMBL | United States | Contour Aviation | 2× daily |
| MissoulaMSO | United States | American Airlines, Envoy Air, United Airlines | 2× daily |
| MonterreyMTY | Mexico | United Airlines, VivaAerobus | 2× daily |
| Punta CanaPUJ | Dominican Republic | American Airlines, Arajet, United Airlines | 2× daily |
| QuebecYQB | Canada | American Airlines, United Airlines | 2× daily |
| SaginawMBS | United States | Libyan Airlines, SkyWest Airlines, United Airlines | 2× daily |
| SpokaneGEG | United States | American Airlines, United Airlines | 2× daily |
| BurlingtonBRL | United States | Contour Aviation | 2× daily |
| Champaign/UrbanaCMI | United States | American Airlines, Envoy Air | 2× daily |
| PensacolaPNS | United States | American Airlines, Envoy Air, United Airlines | 2× daily |
| TorontoYTZ | Canada | Air Canada | 2× daily |
| WinnipegYWG | Canada | United Airlines | 2× daily |
| El PasoELP | United States | American Airlines, Envoy Air, United Airlines | 2× daily |
| ManhattanMHK | United States | American Airlines, Envoy Air | 2× daily |
| MarionMWA | United States | Contour Aviation | 2× daily |
| San JoseSJC | United States | United Airlines | 2× daily |
| Bloomington/NormalBMI | United States | American Airlines, Envoy Air | 2× daily |
| DohaDOH | Qatar | Qatar Airways | 2× daily |
| Eau ClaireEAU | United States | SkyWest Airlines, United Airlines | 2× daily |
| Hilton HeadHHH | United States | American Airlines, Envoy Air, United Airlines | 2× daily |
| Hong KongHKG | Hong Kong | AAE, Cathay Pacific | 2× daily |
| HonoluluHNL | United States | United Airlines | 2× daily |
| LancasterLNS | United States | United Airlines | 2× daily |
| Mason CityMCW | United States | SkyWest Airlines, United Airlines | 2× daily |
| MilanMXP | Italy | Qatar Airways, United Airlines | 2× daily |
| MuskegonMKG | United States | Denver Air Connection | 2× daily |
| TaipeiTPE | Taiwan | China Airlines, EVA Air | 2× daily |
| WarsawWAW | Poland | LOT - Polish Airlines | 2× daily |
| AmmanAMM | Jordan | Royal Jordanian | 2× daily |
| EvansvilleEVV | United States | American Airlines, Envoy Air | 2× daily |
| KalamazooAZO | United States | American Airlines | 2× daily |
| OntarioONT | United States | American Airlines, United Airlines | 2× daily |
| OwensboroOWB | United States | Contour Aviation | 2× daily |
| Billings Metropolitan AreaBIL | United States | American Airlines, Envoy Air, United Airlines | Daily |
| BrusselsBRU | Belgium | Qatar Airways, United Airlines | Daily |
| Key WestEYW | United States | American Airlines, Envoy Air, United Airlines | Daily |
| RenoRNO | United States | United Airlines | Daily |
| Cape GirardeauCGI | United States | Contour Aviation | Daily |
| DecaturDEC | United States | SkyWest Airlines, United Airlines | Daily |
| IronwoodIWD | United States | Denver Air Connection | Daily |
| Limerick citySNN | Ireland | United Airlines | Daily |
| MoreliaMLM | Mexico | Volaris | Daily |
| Santa BarbaraSBA | United States | United Airlines | Daily |
| TokyoHND | Japan | JAL, United Airlines | Daily |
| Addis AbabaADD | Ethiopia | Ethiopian Airlines | Daily |
| BogotáBOG | Colombia | Avianca | Daily |
| Bristol/Johnson/KingsportTRI | United States | American Airlines, Envoy Air | Daily |
| ClarksburgCKB | United States | SkyWest Airlines, United Airlines | Daily |
| CopenhagenCPH | Denmark | SAS | Daily |
| DubaiDXB | United Arab Emirates | Emirates | Daily |
| EdinburghEDI | United Kingdom | United Airlines | Daily |
| ErieERI | United States | American Airlines | Daily |
| EugeneEUG | United States | United Airlines | Daily |
| FairbanksFAI | United States | United Airlines | Daily |
| Idaho FallsIDA | United States | American Airlines, United Airlines | Daily |
| KearneyEAR | United States | SkyWest Airlines, United Airlines | Daily |
| LewisburgLWB | United States | American Airlines | Daily |
| Montego BayMBJ | Jamaica | American Airlines | Daily |
| NanjingNKG | China | Suparna Airlines | Daily |
| NápoliNAP | Italy | American Airlines | Daily |
| PaducahPAH | United States | SkyWest Airlines, United Airlines | Daily |
| São PauloGRU | Brazil | United Airlines | Daily |
| Sarasota/BradentonSRQ | United States | United Airlines | Daily |
| Sioux CitySUX | United States | SkyWest Airlines, United Airlines | Daily |
| Staunton/Waynesboro/HarrisonburgSHD | United States | American Airlines | Daily |
| ValparaisoVPS | United States | American Airlines, Envoy Air | Daily |
| BismarckBIS | United States | American Airlines, Envoy Air | Daily |
| FresnoFAT | United States | United Airlines | Daily |
| Guatemala CityGUA | Guatemala | Avianca, Avianca Costa Rica, United Airlines | Daily |
| JacksonMKL | United States | Denver Air Connection | Daily |
| JohnstownJST | United States | American Airlines, Libyan Airlines, SkyWest Airlines, United Airlines | Daily |
| LynchburgLYH | United States | SkyWest Airlines, United Airlines | Daily |
| QuincyUIN | United States | Contour Aviation | Daily |
| SalinaSLN | United States | United Airlines | Daily |
| ViennaVIE | Austria | Austrian | Daily |
| ChicagoMDW | United States | JRE, RVJ, VJA | 6× weekly |
| Fort DodgeFOD | United States | United Airlines | 6× weekly |
| GuangzhouCAN | China | CSG | 6× weekly |
| HaileySUN | United States | United Airlines | 6× weekly |
| Jebel AliDWC | United Arab Emirates | Emirates | 6× weekly |
| JoplinJLN | United States | United Airlines | 6× weekly |
| KirksvilleIRK | United States | Contour Aviation | 6× weekly |
| KrakówKRK | Poland | LOT - Polish Airlines | 6× weekly |
| MontroseMTJ | United States | United Airlines | 6× weekly |
| MorgantownMGW | United States | United Airlines | 6× weekly |
| Santa FeSAF | United States | American Airlines | 6× weekly |
| ShenzhenSZX | China | CSG | 6× weekly |
| HalifaxYHZ | Canada | American Airlines, Envoy Air, United Airlines | 5× weekly |
| HelsinkiHEL | Finland | Finnair | 5× weekly |
| LafayetteLAF | United States | American Airlines, United Airlines | 5× weekly |
| LisbonLIS | Portugal | TAP Air Portugal | 5× weekly |
| New HavenHVN | United States | Avelo Airlines | 5× weekly |
| SilaoBJX | Mexico | Volaris | 5× weekly |
| BelgradeBEG | Serbia | Air Serbia | 4× weekly |
| CairoCAI | Egypt | EgyptAir | 4× weekly |
| GeorgetownGCM | Cayman Islands | United Airlines | 4× weekly |
| NantucketACK | United States | American Airlines, United Airlines | 4× weekly |
| NassauNAS | Bahamas | United Airlines | 4× weekly |
| OranjestadAUA | Aruba | United Airlines | 4× weekly |
| OsakaKIX | Japan | China Airlines, EVA Air | 4× weekly |
| QuerétaroQRO | Mexico | Volaris | 4× weekly |
| San José del CaboSJD | Mexico | American Airlines, United Airlines | 4× weekly |
| Chicago/West ChicagoDPA | United States | United Airlines | 3× weekly |
| EdmontonYEG | Canada | United Airlines | 3× weekly |
| HyannisHYA | United States | American Airlines | 3× weekly |
| QuitoUIO | Ecuador | Emirates, Turkish Airlines | 3× weekly |
| RhinelanderRHI | United States | United Airlines | 3× weekly |
| Santa ClaraSAL | El Salvador | Avianca | 3× weekly |
| Sault Ste MarieCIU | United States | SkyWest Airlines, United Airlines | 3× weekly |
| SheboyganSBM | United States | — | 3× weekly |
| TokonameNGO | Japan | China Airlines | 3× weekly |
| XiamenXMN | China | — | 3× weekly |
| Wisconsin RapidsISW | United States | United Airlines | 3× weekly |
| ButlerBTP | United States | VJA | 2× weekly |
| DallasDAL | United States | JRE | 2× weekly |
| DubuqueDBQ | United States | Breeze Airways | 2× weekly |
| EagleEGE | United States | United Airlines | 2× weekly |
| FussaOKO | Japan | — | 2× weekly |
| GlasgowPIK | United Kingdom | Air France | 2× weekly |
| HahnHHN | Germany | Silk Way West | 2× weekly |
| Lake CityLCQ | United States | United Airlines | 2× weekly |
| LiberalLBL | United States | VJA | 2× weekly |
| Martha's VineyardMVY | United States | American Airlines | 2× weekly |
| BaudetteBDE | United States | — | Weekly |
| BransonBKG | United States | — | Weekly |
| Bullhead CityIFP | United States | Sun Country Airlines | Weekly |
| CharlestonCRW | United States | SkyWest Airlines | Weekly |
| CincinnatiLUK | United States | — | Weekly |
| CodyCOD | United States | United Airlines | Weekly |
| CologneCGN | Germany | JBD | Weekly |
| DenverAPA | United States | MJS | Weekly |
| ElkhartEKI | United States | — | Weekly |
| EzhouEHU | China | — | Weekly |
| HamiltonYHM | Canada | — | Weekly |
| HoustonSGR | United States | — | Weekly |
| Iron Mountain / KingsfordIMT | United States | — | Weekly |
| JanesvilleJVL | United States | COL | Weekly |
| JuneauJNU | United States | Alaska Airlines | Weekly |
| KahuluiOGG | United States | United Airlines | Weekly |
| LawrencevilleLZU | United States | Libyan Airlines | Weekly |
| LiègeLGG | Belgium | — | Weekly |
| MontereyMRY | United States | United Airlines | Weekly |
| MuskokaYQA | Canada | JRE | Weekly |
| Pinehurst/Southern PinesSOP | United States | — | Weekly |
| Saint LouisSUS | United States | NXC | Weekly |
| San BernardinoSBD | United States | Silk Way West | Weekly |
| St. GeorgeSGU | United States | United Airlines | Weekly |
| TellurideTEX | United States | — | Weekly |
| Westhampton BeachFOK | United States | JRE | Weekly |
| ZaragozaZAZ | Spain | Ethiopian Airlines | Weekly |
| ZhengzhouCGO | China | — | Weekly |
Chicago O'Hare International Airport has nonstop flights to 301 destinations in 43 countries. The most frequently served are Los Angeles, Boston, New York, Dallas-Fort Worth, Atlanta.
76 airlines operate scheduled nonstop routes from ORD. Ranked by number of nonstop destinations the largest are United Airlines, American Airlines, Envoy Air, SkyWest Airlines, Delta Air Lines. United Airlines serves 193 of them.
Yes. 83 of the 301 nonstop destinations from ORD are outside the United States, reaching 41 countries. The busiest international routes are Toronto, Montreal, London.
Los Angeles (LAX) is the most frequently served nonstop destination from ORD, with about 30 flights a day.
Hong Kong (HKG) is the most distant nonstop destination from ORD, about 12,523 km (7,781 miles) away.